Welcome to the NERD Lab, in the Department of Psychiatry at the University of North Carolina at Chapel Hill.

Our lab studies the neuroendocrine mechanisms that influence mood across the female reproductive lifespan, including pubertal and menopausal transitions. To do so, we utilize a multimodal approach that combines the precise measurement of hormone fluctuations and neurophysiological responses to stress and emotion with frequent assessments of mood and interpersonal stress. We aim to understand how social, emotional, cognitive, and neuroendocrine factors interact to produce affective symptoms in females during pivotal developmental windows.

Learn more about our studies!

Mood changes during puberty?

The EVOLVE Study is recruiting adolescents assigned female sex at birth between the ages of 11 and 14 who have had their first period within the last year, are undergoing a healthy pubertal transition, and are not currently taking any prescription medications (including hormonal contraceptives).

Learn more and find out if your child is eligible here!

The AMPT Study is recruiting adolescents ages 12-14 who are experiencing greater stress and mood during the pubertal transition and are not currently taking any prescription medications that alter mood or hormones. Must have a personal mobile device to participate.

Learn more and find out if your child is eligible here!

The Teen Cycle Study is recruiting teens assigned female sex at birth between the ages of 14 and 19 who have had difficulties with depression, suicidal thoughts, self-harm, or related symptoms.

Learn more and find out if your child is eligible here!

Mood changes during menopause?

The WISE Study is recruiting women ages 45-59 who are medically healthy in the menopause transition (having irregular or skipped periods) and are currently experiencing mood changes, particularly irritability.

Learn more and find out if you are eligible here!